abstract：:These studies were undertaken to assess the effects of chronic administration of cerulein plus secretin, every 8 h for 10 days on fluid, protein, and somatostatin-like immunoreactivity (SLI) outputs in rat pancreatic juice. Pancreatic secretion was studied with conscious, cannulated rats, during infusion of precollect...

journal_title：Pancreas

authors： Sarfati P,Green GM,Morisset J

更新日期：1988-01-01 00:00:00

abstract：:A 62-year-old Chinese woman suffering from pancreatic carcinoma coexisting with chronic calcifying pancreatitis is reported. Ultrasonography and computed tomography disclosed multiple intraductal calcifications in the pancreatic head and body and a tumor at the tail. Laparotomy revealed cancerous peritonitis in additi...

journal_title：Pancreas

authors： Lin JT,Wang TH,Chen DS,How SW,Lai MY,Chen JC,Sung JL

更新日期：1988-01-01 00:00:00

abstract：:A new model is proposed for pancreatic enzyme secretion in response to food protein intake in rats. We have found a novel peptide in rat bile-pancreatic juice, which exhibits a trypsin-sensitive, cholecystokinin (CCK)-releasing activity. The amino acid sequence of the peptide purified from rat bile-pancreatic juice is...

journal_title：Pancreas

authors： Iwai K,Fushiki T,Fukuoka S

更新日期：1988-01-01 00:00:00

abstract：:To determine the role of endogenous pancreatic polypeptide (PP) as a physiological inhibitor of pancreatic secretion, normal rabbit serum (control) or rabbit PP-antiserum was administered intravenously to dogs with chronic esophageal, gastric, and pancreatic fistulas. In all dogs tested, sham-feeding and ordinary feed...

journal_title：Pancreas

authors： Konturek SJ,Bielański W,Kwiecień N,Konturek J,Czarnobilski K

更新日期：1987-01-01 00:00:00

abstract：:Scanning electron microscopy (SEM) and energy dispersive x-ray fluorescence (EDXRF) have been used in this study to investigate the morphology, nature, and arrangement of major, minor, and trace elements in human pancreatic calculi (PC) obtained from patients with alcoholic and tropical pancreatitis. The present study...

journal_title：Pancreas

authors： Pitchumoni CS,Viswanathan KV,Gee Varghese PJ,Banks PA

更新日期：1987-01-01 00:00:00

abstract：:Dogs with chronic pancreatic fistulae were given 0.5 ml of nonimmune rabbit serum or antibody S5, an antibody raised against the C-terminal pancreatic polypeptide (PP) hexapeptide. A 3-h infusion of secretin (125 ng/kg/h) and CCK8 (50 ng/kg/h) was started 30 min after injecting serum. Exogenous BPP (400 pmol/kg/h) was...

journal_title：Pancreas

authors： Fink AS,Gilbert S,Green H,Taylor IL

更新日期：1987-01-01 00:00:00

abstract：:Peptide YY (PYY) is a recently isolated gut peptide that is found primarily in the mucosal endocrine cells of the terminal ileum, colon, and rectum of several mammalian species, including humans. The purpose of this study was to characterize the effect of PYY on pancreatic exocrine secretion in six conscious dogs prep...

journal_title：Pancreas

authors： Lluis F,Gomez G,Fujimura M,Greeley GH Jr,Thompson JC

更新日期：1987-01-01 00:00:00

abstract：:The influence of pancreatic secretions on growth and brush-border enzyme activity, throughout the entire small intestine, was examined in the rat. Pancreatic secretions were excluded from the gut lumen by stapling the pancreatic ducts, without interruption of bile flow. The entire small intestine was studied as four s...

journal_title：Pancreas

authors： Hauer-Jensen M,Christensen K,Wilson HD,Schedl HP

更新日期：1987-01-01 00:00:00

abstract：:The present investigation provides follow-up data (up to 36 months) of exocrine and endocrine pancreatic function, inflammatory activity, pain, and body weight in 23 chronic pancreatitis patients submitted to Whipple's procedure plus intraoperative Ethibloc occlusion of the remaining pancreatic duct system between Jan...

journal_title：Pancreas

authors： Schneider MU,Meister R,Domschke S,Zirngibl H,Strebl H,Heptner G,Gebhardt C,Gall FP,Domschke W

更新日期：1987-01-01 00:00:00

abstract：:Atrial natriuretic factor (ANF) binding sites in adult rat exocrine pancreas were studied by autoradiography using slide-mounted frozen tissue sections with mono-iodinated ANF (101-126) as the tracer. Radiolabel was displaced by unlabeled atrial peptide (IC50 = 2 X 10(-11) M). High specific labeling was found in pancr...

journal_title：Pancreas

authors： Chabot JG,Morel G,Kopelman H,Belles-Isles M,Heisler S

更新日期：1987-01-01 00:00:00

abstract：:To assess the role of stapling devices and routine gastroenterostomy in palliative bypass surgery, the hospital records of 150 consecutive patients with unresectable, histologically proven pancreatic adenocarcinoma requiring palliative bypass procedure were reviewed. During recent years staplers have gained increasing...

journal_title：Pancreas

authors： Kairaluoma MI,Kiviniemi H,Laitinen S,Ståhlberg M

更新日期：1987-01-01 00:00:00

abstract：:Pancreatic duct fragments were isolated from rat and hamster pancreas and were cultured in an agarose matrix for up to 8 weeks (rat) or 20 weeks (hamster). The fragments consisted predominantly of duct epithelium, lesser numbers of stromal and atrophied acinar cells, and small numbers of islet cells. Hamster ducts ave...

journal_title：Pancreas

authors： Githens S,Finley JJ,Patke CL,Schexnayder JA,Fallon KB,Ruby JR

更新日期：1987-01-01 00:00:00

abstract：:We collected pure pancreatic juice during an entire day and examined pancreatic secretory changes induced by ordinary meals in a male patient having an external drainage of the main pancreatic duct. The ingestion of breakfast, lunch, and dinner each caused a marked increase in pancreatic secretion above basal levels. ...

journal_title：Pancreas

authors： Gullo L,Pezzilli R,Priori P,Baldoni F,Paparo F,Mattioli G

更新日期：1987-01-01 00:00:00

abstract：:We have studied the degree of pancreatic secretory alterations assessed by secretin-cerulein test (S-C) in relation to various morphological changes detected by real-time ultrasonography (US) in 42 patients affected by chronic pancreatitis. Exocrine insufficiency was found in 41 patients (97.6%), while morphological a...

journal_title：Pancreas

authors： Bolondi L,Priori P,Gullo L,Santi V,Li Bassi S,Barbara L,Labó G

更新日期：1987-01-01 00:00:00

abstract：:The effect of surgical celiac and superior mesenteric ganglionectomy (GGX) on intrinsic pancreatic innervation was studied in male Wistar rats. Neurons were stained in the pancreas of control and ganglionectomized rats with histochemical methods evidencing the acetylcholinesterase (AChE) activity and the induced fluor...

journal_title：Pancreas

authors： Anglade P,Michel C,Rozé C

更新日期：1987-01-01 00:00:00

abstract：:Utilizing scanning electron microscopy and isolated, vascularly perfused rat pancreas, we studied the angioarchitecture and the effect of the insulinotropic hormone, gastric inhibitory polypeptide (GIP), on cholecystokinin (CCK)-stimulated exocrine secretion. We tried to correlate the microcirculation with the physiol...

journal_title：Pancreas

authors： Mueller MK,Scheck T,Dreesmann V,Miodonski A,Goebell H

更新日期：1987-01-01 00:00:00

abstract：:Amyloid was isolated from islets of amyloidotic pancreata of monkey and human beings by solubilization of non-amyloid materials from the pancreas and digestion of contaminating collagen and elastin. The resulting pellet was estimated to be greater than 90% pure islet amyloid. Antibodies specific for monkey islet amylo...

journal_title：Pancreas

authors： Fang TY,Howard CF Jr

更新日期：1986-01-01 00:00:00

abstract：:We simultaneously measured hepatic insulin removal invasively and estimated hepatic clearance and extraction of insulin pharmacokinetically from cardiac output and peripheral plasma concentrations (relatively) noninvasively. The invasive methods involved continuous electromagnetic measurements of portal venous and hep...

journal_title：Pancreas

authors： Berzins R,Tam YK,Molnar GD,Rajotte RV,Wieczorek KR,McGregor JR,Fawcett DM

更新日期：1986-01-01 00:00:00

abstract：:In the present study, antibodies directed against clathrin light (33 kDa-36 kDa) and heavy (180 kDa) chains were used to confirm, by immunocytochemistry, that coated vesicles increase in number in the exocrine cells of pancreatic lobules incubated under anoxic (N2) conditions. The same antibodies were used to check wh...

journal_title：Pancreas

authors： Merisko EM,Farquhar MG,Palade GE

更新日期：1986-01-01 00:00:00

abstract：:Conscious rats were infused with optimal doses of secretin (16 clinical units [CU]/kg/h), cerulein (0.25 microgram/kg/h), and both for varying periods of time over 24 h. The presence of zymogen granules in acinar cells and the tissue content of enzymes showed progressive decreases over 3 and 12 h for cerulein and secr...

journal_title：Pancreas

authors： Rausch U,Rüdiger K,Vasiloudes P,Kern H,Scheele G

更新日期：1986-01-01 00:00:00

abstract：:The effects of coffee on exocrine pancreatic secretion are unknown but may be important, because a link between chronic stimulation of pancreatic secretion and experimental chemical carcinogenesis and an association between coffee drinking and human pancreatic adenocarcinoma have been reported. We measured exocrine pa...

journal_title：Pancreas

authors： Coffey RJ,Go VL,Zinsmeister AR,DiMagno EP

更新日期：1986-01-01 00:00:00

abstract：:The clinical, diagnostic, and therapeutic aspects of 27 patients with pancreatopleural fistula (PPF) reported in the literature, and two additional patients managed by the authors, form the basis of this report. The diagnosis of PPF is based on the triad of massive pleural effusions, elevated pleural fluid amylase, an...

journal_title：Pancreas

authors： Bedingfield JA,Anderson MC

更新日期：1986-01-01 00:00:00

abstract：:In 134 consecutive patients with acute abdominal pain, we evaluated the clinical role of a new rapid test for serum lipase based on latex agglutination. The results were compared with those obtained with a widely used lipase immunoassay as well as with serum amylase and pancreatic isoamylase measurements. Fifty-five h...

journal_title：Pancreas

authors： Ventrucci M,Pezzilli R,Naldoni P,Montone L,Gullo L

更新日期：1986-01-01 00:00:00

abstract：:Pancreatic insufficiency was induced in rats by a single injection of 50 microliter oleic acid into the pancreatic duct over a period of 3 min. Exocrine tissue was destroyed within 3-6 days, and after 6 weeks the remaining pancreas equaled 2.7% of the original organ. The rats showed retardation of body weight in spite...

journal_title：Pancreas

authors： Mundlos S,Adler G,Schaar M,Koop I,Arnold R

更新日期：1986-01-01 00:00:00

abstract：:To examine previous work carried out at a single center, i.e., France, on the pathologic features of chronic pancreatitis and to examine geographic differences, 359 cases of chronic pancreatitis from five centers were studied pathologically and the results analyzed according to appropriate statistical methods. It was ...

journal_title：Pancreas

authors： Sahel J,Cros RC,Durbec JP,Sarles H,Bank S,Marks IN,Bettarello A,Duarte I,Guarita D,Machado M

更新日期：1986-01-01 00:00:00

abstract：:The transport specificity of L-glutamine influx in the perfused rat exocrine pancreas has been investigated using a dual isotope tracer dilution technique. During a single circulation through the isolated pancreas, an epithelial uptake of 71 +/- 1% (n = 10) was measured for L-(3H)glutamine relative to the extracellula...

journal_title：Pancreas

authors： Mann GE,Habara Y,Peran S

更新日期：1986-01-01 00:00:00